A boorish doctor who has devised a way to bring the dead back to life gets into a car accident and kills his beautiful fiancee; he takes her severed head back to the lab with him and keeps it alive in a tray of serum. She is unhappy with the situation and begs him to let her die, but he embarks upon a search for the perfect body for his amour, visiting strip clubs and streetwalkers and scouring the city. Meanwhile, the fiancee discovers that a side effect of her current status is telepathy, and she begins to communicate with the doctor's "mistake," which is held captive in a locked room off the lab. With the monster's help, the bodyless woman manages to save the life of the doctor's chosen victim and burn the lab down in the process.