Natsume Kiroemon, the protagonist, was the 45th leader of the Natsume family, and inherit the "Kiryuu no Mimi ", a tool which gave its bearer easy access to wealth and women. As a result of his father's death, he left the Italian monastery where he'd been training and rightfully took the name "Natsume Kiroemon" as well as the power of the Kiryuu no Mimi.
The evil hand of the Mina family attacked Natsume constantly and abducted Kanako. Now Natsume has unlocked the seal, making the Kiryuu's power surge, and he's striking back at the Mina family.