内科と外科を統一した「メディカルソリューション本部」を立ち上げ、医療体制を一新した「東帝大学病院」。本部長の座に就いた蜂須賀隆太郎（野村萬斎）は内科治療の優先、ならびに外科手術については自らの息がかかった外科医・興梠広（要潤）を中心に行うことを、高らかに宣言する。
そんな中、愛想はすこぶる悪いが、腕は超一流のフリーランス看護師・那須田灯（松下奈緒）が、「東帝大学病院」に雇われることになった。灯はさっそく、興梠が執刀医を務める記者・五木和男（井上肇）の直腸がん手術で、オペ看を担当。興梠の指示を待つことなく、次々と的確な器械を差し出す。ところが、そんな灯に憤慨した興梠はナースステーションに連絡を入れ、今すぐオペ看をチェンジするよう要求。応対した看護師・大間正子（今田美桜）は、慌てて手術室へ向かう。
やがて手術は終了。ところが翌日、五木が激しい腹痛を訴え、再手術が必要な状態に陥った！ オペに何か問題があったと考えた大門未知子（米倉涼子）は、急いで原因を突き止めようとする。ところが…存在するはずのオペの録画データは、なぜか消失。未知子は灯を捕まえ、途中でオペ看を外された理由を尋ねるが、灯はただただ無愛想に口をつぐみ…!?
さらに、事態はとんでもない方向へと転ぶ。未知子に問い詰められた興梠が、手術ミスをしたのは正子だと主張し始めたのだ。一方、灯もなぜかこの一件に対して無関心な態度を固持。依然として何も語ろうとせず…！
"Totei University Hospital" has renewed its medical system by launching the "Medical Solution Headquarters" that unifies internal medicine and surgery. Ryutaro Hachisuka (Mansai Nomura), who took the position of general manager, proclaims that medical treatment should be prioritized and that surgery should be performed mainly by the surgeon, Jun Kaname, who took his breath. .. Meanwhile, her amiability is very bad, but her arm is hired by a top-notch freelance nurse, Akira Nasuda (Nao Matsushita), at "Totei University Hospital". Akari was in charge of the operation for rectal cancer surgery by Kazuo Itsuki (Hajime Inoue), a reporter whose surgeon is Kobuki. Without waiting for Kobuki's instructions, she presents the right instruments one after another. The nurse, Masako Oma (Mio Imada), who responded to her, hurriedly headed to her operating room. Soon the surgery was completed. However, the next day, Itsuki complained of severe abdominal pain requiring reoperation!
내과와 외과를 통일한 ′메디컬 솔루션 본부′가 설립되고 의료 체제를 새롭게 바꾼 ′토테이 대학 병원′. 본부장 자리에 앉은 하치스카는 내과 치료의 우선 및 외과 수술에 대해선 외과의 코오로기를 중심으로 실시한다는 것을 선언한다. 그러던 중, 붙임성은 너무 없지만 실력은 일류인 프리랜서 간호사 나스다가 ′토테이 대학 병원′에 고용됐다. 나스다는 바로 코오로기가 집도의를 맡은 수술에서 수술 간호사를 담당하게 된다. 코오로기의 지시를 기다리지 않고 잇따라 정확한 기구를 꺼내놓는 나스다. 그런 나스다에게 분노한 코오로기는 간호사 교체를 요청하는데...
