Nicola has been diagnosed with ten different conditions, including fibromyalgia, ME, sciatica and depression. Her pain and exhaustion has led her to become addicted to painkillers and almost housebound. Can Dr Chatterjee help Nicola find the cause of her problems and improve her health so that she can enjoy life with her three young sons again? Laverne suffers from stress and severe exhaustion, and is at risk of developing life-threatening type 2 diabetes. A single mother, she works two jobs as a car saleswoman and a nightclub bouncer, while juggling the demands of her two young sons. Rangan must find a way to completely overhaul her lifestyle, including her diet, sleeping habits and work-life balance.