The team of health professionals visits the Kelly family in Kildare, where soon-to-be 40-year-old twins Ashling and Aileen live with their mum, Christine, who has type two diabetes. Both twins are overweight, with one sister having a sweet tooth, and the other relying on alcohol. After being screened and monitored, the girls are given a frank assessment, then they have eight weeks to change their lifestyle before being retested.