Missy and her team at American Family Bioclean battle bugs, biohazard, and piles of trash to clean a home and create a safe space for a client's sick wife to come home to. Meanwhile, Python and Margred at Amanda's Cleaning Service unseal a Cold War bunker that's going to need an atomic cleaning if it's ever to be used again.
Missy and her family have to save a house that's filled floor to ceiling with trash and toxins from birds, cats and other surprises. The clock is ticking as they work to sanitize and deodorize this maze of messes for their client. Meanwhile, Python and Margred look to expand their business by taking on a ghost pool, but this green monster may not be the best place to learn on the job. No one knows what lurks beneath the surface, and there's only one way to find out.
Missy and her team take on a house that needs to be cleared of toxic biohazards before it can be put on the market, but even Josh "The Poo Man" may not be able to get this house clean enough to sell. And Sadie's Pro Cleaning team walks into a scene from the big screen as they take on a massive bio clean that has filthy surprises at every turn
Missy and the team get called in by a city commissioner to help a widow whose home has been overtaken by cats. Feline filth is everywhere, and it's up to the team to make the house safe again for humans. Python and Margred help a wheelchair-bound friend get his childhood home as clean and pure as his fondest memories.