Featured performances and roasts by Jim Breuer, Mario Cantone, Lenny Clarke, Doctor Dre, Dane Cook, Nick DiPaolo, Adam Ferrara, Michael J. Fox, Peter Gallagher, Don Gavin, Gina Gershon, Gilbert Gottfried as Denis' Irish Wolfhound, Ed Lover, Joe Mantegna, Conan O'Brien, Colin Quinn, Rene Russo, and Christopher Walken.
| Name | Type | Role | |
|---|---|---|---|
| Denis Leary | Producer | ||
| Jim Serpico | Producer | ||
| Colin Quinn | Guest Star | ||
| Dane Cook | Guest Star | ||
| Don Gavin | Guest Star | ||
| Mario Cantone | Guest Star | ||
| Rene Russo | Guest Star | ||
| Adam Ferrara | Guest Star | ||
| Gina Gershon | Guest Star | ||
| Lenny Clarke | Guest Star | ||
| Christopher Walken | Guest Star | ||
| Michael J. Fox | Guest Star | ||
| Jeff Garlin | Guest Star | ||
| Gilbert Gottfried | Guest Star | ||
| Dr. Dre | Guest Star | ||
| Nick Di Paolo | Guest Star | ||
| Denis Leary | Guest Star | ||
| Conan O'Brien | Guest Star | ||
| Ed Lover | Guest Star | ||
| Peter Gallagher | Guest Star | ||
| Jim Breuer | Guest Star | ||
| John Fortenberry | Director |