In this special 2-hour series premiere, Chris Jericho, Lucy Lawless, Cheech Marin, Carly Patterson, Alfonso Ribeiro, Jai Rodriguez, Hal Sparks and Lea Thompson are each paired with an established recording artist to compete for a prize of a $100,000 donation to the charity of their choice.
| Name | Type | Role | |
|---|---|---|---|
| Peter Frampton | Guest Star | ||
| Smokey Robinson | Guest Star | ||
| Michael Bolton | Guest Star | ||
| Lee Ann Womack | Guest Star | ||
| Randy Travis | Guest Star | ||
| Gladys Knight | Guest Star | ||
| James Ingram | Guest Star | ||
| Michelle Williams | Guest Star | ||
| Bruce Gowers | Director |