A female jogger is found floating in the Schuylkill River. Dr. Megan Hunt teams up with her partner, medical investigator and former cop Peter Dunlop, under the watchful eye of their boss, Chief Medical Examiner Dr. Kate Murphey, who is very aware of Megan’s gifted but polarizing work style. Megan’s colleagues, Dr. Ethan Gross and Deputy Chief Medical Examiner Dr. Curtis Brumfield, must find their own way to work alongside the new medical examiner. Megan’s investigation takes her out in the field where she meets old-school cop Detective Bud Morris, who is exasperated by Megan’s tenacity and bull-headedness. But his partner, Detective Samantha Baker, possesses a quiet respect for Megan’s input, even if Morris doesn’t. Meanwhile, as she’s is trying to solve the female jogger’s death, Megan has to solve a personal puzzle of her own -- what is the perfect present for her daughter’s 12th birthday?
When a young, interracial couple is found shot and killed inside their car in Fairmont Park, Dr. Megan Hunt promises the grieving parents that their daughter’s killer will be found. Detectives Bud Morris and Samantha Baker are ready to chalk the case up to a murder-suicide, but Megan and her team find evidence on the bodies that sends the case in an entirely different and shocking direction. Meanwhile, Peter advises Megan not to push too hard when it comes to reconnecting with her daughter, Lacey.
When a severed hand and foot turn up in a back alley, Megan and her team must literally piece the victim back together. Meanwhile, Megan's daughter, Lacey, gets her mother's reluctant permission to visit her at the office and film her at work as part of a video essay for Social Studies class. What Lacey learns in the process profoundly changes her view of her mother
After Peter rescues a woman from a house fire, Megan discovers another person in the house who died. Peter takes the discovery personally since he had no idea anyone else was in the house. A veteran arson investigator challenges Megan at each step in her investigation. When Megan complains to Kate the response she gets only intensifies the tension between the two women.
When a popular 17-year-old high school student is found dead after a rave, the team must decipher various unknown drugs in his system and multiple bruises to figure out the cause of death. Megan is finally starting to date again after the divorce but her ex-husband springs some shocking news on her and her daughter, causing tension at home and at work.
A pharmaceutical rep is found dead in the Schuykill River, but when Dr. Megan Hunt and the team investigate, there's no blood found in her body. The team must locate the original crime scene to see if they can find the cause of death, but with suspects who have access to hundreds of unknown drugs, they may never know who or what killed her.
When two young girls are in a tragic car accident, one is left in critical condition and the other is found dead at the scene. As Megan and her team investigate the case, however, they realize there has been an awful mistake. Not only was the wrong girl pronounced dead, but the car accident may not have been the actual cause of death.
In the Season 3 premiere, it's months after Peter's death and Megan returns to work, only to learn she's been teamed with a detective with whom she has a past history. She, Det. Sullivan and his rookie partner are up against a serial killer who targets young war veterans. The stakes become higher after she gets a call from the killer and is told he's holding her teenage daughter, Lacey, hostage.
Megan and Tommy investigate a murder that appears on the surface to be a case of severe child abuse. But the girl's parents claim that their daughter was killed by the Devil after being possessed. The team must try to separate fact from fiction when the victim's mother begs Megan to help her stop the same thing from happening to their surviving daughter.
Megan and Tommy are investigating the death of a convicted murderer who was recently released because of a technicality. So they first check out the husband of the woman he killed. But he has an alibi. Tommy's uncertain if it's important to find out who killed him. But Mrgan reminds him they have to be objective. Later another murderer, who was also released because of a technicality, was also killed. They talk to the wife of the victim and she too has an alibi. They later learn that both the husband and wife go to the same therapist. They think that they conspired to kill the person they want dead but when that doesn't pan out. They realize that they should look at the therapist. And when Megan's mom plans to sell her house, she has Megan come over to get anything she wants and it's while going through the things she learns a secret her mother kept from her.
Gerry Roberts, in trial for defrauding his investors of a billion dollars, is kidnapped in front of the court house. The getaway car runs over a protestor and later, the team has to decide whether a video of Roberts being killed could have been faked by himself. Meanwhile, Megan gets closer to the truth about her father's death.
A schizophrenic teenage girl at a mental institution is found murdered. When Megan and Tommy interview a young patient named Darby, who seems extremely sane and lucid, she tells them that she saw the killer climb down from a heating vent in the ceiling, but most shocking of all -- he meant to kill her, not the actual victim. Could the killer be Dr. Malcolm, the ward director, who is obstructing their investigation.
When a plane crashes in Philadelphia due to a gunman opening fire while aloft, the entire team of Megan, Kate, Tommy, Adam, Curtis, Ethan, Riley and Stafford must go into disaster mode. Since the crash hits the city's main power grid, Megan must conduct autopsies on the victims during frequent blackouts, but then one of the bodies goes missing. Meanwhile, Tommy and Riley are in a serious car accident while trying to investigate.
An inmate violently escapes from a prison transport van and becomes a dangerous fugitive on the run in Philadelphia. Soon another man turns up dead - who's revealed to be a witness in the escaped prisoner's murder trial. Megan must continue to search for the truth in the original case when the accused murderer shows up and pleads with her that he is innocent and being framed.
When a severed hand and foot turn up in a back alley, Megan and her team must literally piece the victim back together. Meanwhile, Megan's daughter, Lacey, gets her mother's reluctant permission to visit her at the office and film her at work as part of a video essay for Social Studies class. What Lacey learns in the process profoundly changes her view of her mother