In Ohio, Truck Hunters Shawn and Vince must track down and deliver a big rig filled with highly classified cargo but mid-route they pick up a mysterious tail. In Texas, a trailer filled with prized cattle is stranded on a track, and Marshall and Korchenko is the trucker's last hope to avert a disastrous collision. In New Jersey, brothers-in-law John and Gene are on the hunt for a hijacked truck full of a million dollars worth of laptops. And in Denver, Animal and Steve discover the perils of trying to deliver a hot load on a tight deadline, as the President's visit locks down the city's traffic grid.