At Leahurst's equine hospital, surgeon Debbie Archer is coming to the end of her shift as emergency is rushed in. Millie, a family's pet horse, is suffering from the life-threatening condition of colic.
Niamh Lewis is looking after one of the newest admissions at the clinic, a pregnant horse called Destiny.
Alex and Shelley are getting ready for a visit from one of their favourite patients which is an over weight bassett hound called Charlie, who has been on a strict weight loss programme for around four months. Neil is greeting his first patient of the day a horse called Monte who needs surgery on his seriously infected sinuses.
Lorien takes a team of students to meet an unusual patient who lives in a back garden. Rusty is a huge friendly kunekune pig whose toenails need to be trimmed. Neil helps Chester Zoo's vet with one of their rarest creatures, an onager named Sophie who is off her food.
At Leahurst, Tim Nuttall has an unusual emergency arrival, a dog called Roxy who is scratching herself to death. Jo Oultram and her students are called out to an emergency calving. At Chester Zoo, vet Steve Unwin has brought in a specialist dentist to help him treat a chimp called Can-Can.
Farm practice vet Helenhas to deal with a big patient with an even huger problem, a bull who is suffering with a badlyinfected abscess on his rear end. Billy the Yorkshire terrier is at the the radiotherapy clinic at the small animal hospital.
An 18-year-old pony called Scrumpy Jack requires surgery to comabt severe colic whilst a bearded collie dog has heart surgery.
Ben follows a difficult operation to pin together a puppy's fractured leg whilst a herd of hefty sheep need some help dealing about their weight.
It is lambing season and farm vet Jo Oultram is called to help a heavily pregnant ewe that has been finsing it hard to give birth. An overweight Newfoundland named Ella is brought in to Leahurst's obesity clinic after after having been overfed.
Jo needs to work quickly to save the life of a dairy cow suffering with a twisted stomach. Peter operates on a miniature schnauzer and the small eyes of a capuchin monkey.
Lindsey attempts to help with a Chinese crested dog with a swollen womb whilst a cat called Miffy needs to have an eye removed. A rat called Marge has lost its sense of balance.