Host Eric Adjepong welcomes three award-winning chefs specializing in Mexican cuisine to the arena. Ray Garcia, Claudette Zepeda and Gustavo Romero are ready to take on Iron Chef Alex Guarnaschelli in a battle celebrating America's neighbors to the South. Chef Alex fights to maintain her dominance against skilled chefs in a cuisine she loves to eat but rarely cooks, but will these skilled chefs be too spicy for Alex to handle? Respected chefs Daniela Soto-Innes and Bricia Lopez judge whether Alex has the expertise to get the better of these Mexican experts in her own house.