人心，是一門深奧科學。人會犯罪，皆因被貪婪、憤怒、嫉妒等情緒支配。法證事務部高級化驗師余星柏以精闢方法找出證據，受熱血女警霍寶英傾慕，譜出一段無法以科學計算的愛情。法醫科高級醫生范佩清冷靜睿智，得流氓醫生秦克男默默守護，衝破困境。重案組高級督察井浩然不眠不休，與斜槓女子譚倩雯互相扶持，追尋真相。面對消失的證據、迷失的困局、狡猾的兇手，法證團隊要還生者公道，替死者雪冤。
Aliases
The human heart is a profound science. People commit crimes because they are dominated by emotions such as greed, anger, and jealousy. Yu Xingbai, a senior chemist of the Forensic Affairs Department, finds out evidence with incisive methods. He is admired by the hot-blooded policewoman Huo Baoying, and composes a love that cannot be calculated scientifically. Fan Peiqing, a senior doctor in the forensic department, is calm and wise, and is silently guarded by the rogue doctor Qin Kenan, breaking through the predicament. Jing Haoran, a senior inspector of the serious crime team, works tirelessly with Tan Qianwen, a slash woman, to support each other and pursue the truth. Facing the disappearing evidence, the lost predicament, and the cunning murderer, the forensic team must restore justice to the living and avenge the grievances of the dead.
人心，是一门深奥的科学。人会犯罪作恶，皆因被贪婪、愤怒、软弱和嫉妒等情绪支配。为了逃避刑责，人会利用谎言掩饰真相，用诡计扰乱视线，令法证工作难上加难。未破的悬案、消失的证据、迷失的困局，都是法证团队面对的一个个难关。纵然过程中会受到打击，但他们都会坚持初心，跌倒之后重新出发，不会放弃追寻真相。
《法证先锋V》的案件和布局更加让人意想不到，唯有靠着“法证部”、“法医科”及“重案组”这灭罪铁三角，秉承前四季的理念，通力合作，找出真凶，还生者公道，替死者雪冤。
