| Name | Type | Role | |
|---|---|---|---|
| GWSN | Musical Guest | "Puzzle Moon", "Outro Performance" | |
| Lee Seo-ryoung | Musical Guest | GWSN - Seoryoung | |
| Lee Know | Musical Guest | Stray Kids - Lee Know | |
| Bae Joon-young | Musical Guest | The Boyz - Jacob | |
| Li Jiajia | Musical Guest | Nature - Gaga | |
| Kim Sun-woo | Musical Guest | The Boyz - Sunwoo | |
| Park Chae-won | Musical Guest | Loona - Go Won | |
| Hwang Min-hyun | Musical Guest | Wanna One - Minhyun | |
| Jeon Hee-jin | Musical Guest | Loona - HeeJin | |
| Bae Jin-young | Musical Guest | Wanna One - Jinyoung | |
| Wang Chingyi | Musical Guest | GWSN - SoSo | |
| Choi Ye-na | Musical Guest | Iz*One - Yena | |
| Ji Chang-min | Musical Guest | The Boyz - Q | |
| Song Ha-young | Musical Guest | Fromis 9 - Hayoung | |
| Roh Ji-sun | Musical Guest | Fromis 9 - Jisun | |
| Wanna One | Musical Guest | "Hide And Seek", "Spring Breeze" | |
| Abe Haruno | Musical Guest | Nature - Haru | |
| Ong Seong-wu | Musical Guest | Wanna One - Seongwu | |
| Kim Jung-eun | Musical Guest | Loona - Kim Lip | |
| Seo Soo-jin | Musical Guest | (G)I-dle - Soojin | |
| Honda Hitomi | Musical Guest | Iz*One - Hitomi | |
| Bang Chan | Musical Guest | Stray Kids - Bang Chan | |
| Seungmin | Musical Guest | Stray Kids - Seungmin | |
| Younghoon | Musical Guest | The Boyz - Younghoon | |
| Miyauchi Haruka | Musical Guest | GWSN - Miya | |
| Kim Sae-rok | Musical Guest | Nature - Saebom | |
| Ahn Hyeong-seop | Musical Guest | Hyeongseop X Euiwoong - Hyeongseop | |
| Son Hye-ju | Musical Guest | Loona - Olivia Hye | |
| Lee Seo-yeon | Musical Guest | Fromis 9 - Seoyeon | |
| Kim Hyun-jin | Musical Guest | Loona - HyunJin | |
| Park Woo-jin | Musical Guest | Wanna One - Woojin | |
| Kang Lena | Musical Guest | GWSN - Lena | |
| An Yu-jin | Musical Guest | Iz*One - Yujin | |
| Ju Hak-nyeon | Musical Guest | The Boyz - Ju Haknyeon | |
| Kang Ye-jin | Musical Guest | Nature - Loha | |
| Han | Musical Guest | Stray Kids - Han | |
| Lee Byeong-jae | Musical Guest | Vinxen | |
| i-dle | Musical Guest | "Hann (Alone)", "Latata" | |
| Choi Ye-rim | Musical Guest | Loona - Choerry | |
| Kim Jae-hwan | Musical Guest | Wanna One - Jaehwan | |
| Song Yuqi | Musical Guest | (G)I-dle - Yuqi | |
| Kim Chae-won | Musical Guest | Iz*One - Chaewon | |
| Changbin | Musical Guest | Stray Kids - Changbin | |
| Jang Won-young | Musical Guest | Iz*One - Wonyoung | |
| Lee Jae-hyun | Musical Guest | The Boyz - Hyunjae | |
| Kim Seo-kyoung | Musical Guest | GWSN - Seokyoung | |
| Stray Kids | Musical Guest | "Like Ooh-Ahh" (orig. by Twice), "My Pace" | |
| Wáng Mèngyú | Musical Guest | Nature - Aurora | |
| Lee Eui-woong | Musical Guest | Hyeongseop X Euiwoong - Euiwoong | |
| Jeong Jin-sol | Musical Guest | Loona - JinSoul | |
| Cho Ha-seul | Musical Guest | Loona - HaSeul | |
| Lee Dae-hwi | Musical Guest | Wanna One - Daehwi | |
| Kim Sun-woo | Musical Guest | The Boyz - Sunwoo | |
| Kim Dong-han | Musical Guest | Kim Dong-han | |
| Nako Yabuki | Musical Guest | Iz*One - Nako | |
| Woo Hye-jun | Musical Guest | Nature - Uchae | |
| Hyunjin | Musical Guest | Stray Kids - Hyunjin | |
| Moon Hyung-seo | Musical Guest | The Boyz - Kevin | |
| Marion Rambu Jola Pedy | Musical Guest | Marion Jola | |
| Ha Soo-young | Musical Guest | Loona - Yves | |
| Yoon Ji-sung | Musical Guest | Wanna One - Jisung | |
| Lee Chae-young | Musical Guest | Fromis 9 - Chaeyoung | |
| Yeh Shuhua | Musical Guest | (G)I-dle - Shuhua | |
| Kim Min-ju | Musical Guest | Iz*One - Minju | |
| Felix | Musical Guest | Stray Kids - Felix | |
| Lee Seo-young | Musical Guest | GWSN - Anne | |
| Miyawaki Sakura | Musical Guest | Iz*One - Sakura | |
| Lee Ju-yun | Musical Guest | The Boyz - Juyeon | |
| Lee Sae-rom | Musical Guest | Fromis 9 - Saerom | |
| fromis_9 | Musical Guest | "Love Bomb", "My Type" (orig. by iKon) | |
| Im Ha-young | Musical Guest | Nature - Lu | |
| Jang Gyu-ri | Musical Guest | Fromis 9 - Gyuri | |
| Im Yeo-jin | Musical Guest | Loona - YeoJin | |
| Park Ji-hoon | Musical Guest | Wanna One - Jihoon | |
| Kwon Eun-bi | Musical Guest | Iz*One - Eunbi | |
| Eric | Musical Guest | The Boyz - Eric | |
| Cho Mi-yeon | Musical Guest | (G)I-dle - Miyeon | |
| Kim Dong-han | Musical Guest | Donghan | |
| Kim Min-jung | Musical Guest | Nature - Sunshine | |
| I.N | Musical Guest | Stray Kids - I.N | |
| Lee Sang-yeon | Musical Guest | The Boyz - Sangyeon | |
| Jeon So-yeon | Musical Guest | (G)I-dle - Soyeon | |
| Kim Ji-woo | Musical Guest | Loona - Chuu | |
| Lai Guanlin | Musical Guest | Wanna One - Kuanlin | |
| Baek Ji-heon | Musical Guest | Fromis 9 - Jiheon | |
| Ha Sung-woon | Musical Guest | Wanna One - Sungwoon | |
| Lee Chae-yeon | Musical Guest | Iz*One - Chaeyeon | |
| Kang Min-ju | Musical Guest | GWSN - Minju | |
| Jo Yu-ri | Musical Guest | Iz*One - Yuri | |
| Choi Chan-hee | Musical Guest | The Boyz - New | |
| Lee Na-gyung | Musical Guest | Fromis 9 - Nagyung | |
| Park Ji-won | Musical Guest | Fromis 9 - Jiwon | |
| THE BOYZ | Musical Guest | "Boy", "Right Here" | |
| Choi Yu-bin | Musical Guest | Nature - Chaebin | |
| VIVI | Musical Guest | Loona - ViVi | |
| Kang Daniel | Musical Guest | Wanna One - Daniel | |
| Nicha Yontararak | Musical Guest | (G)I-dle - Minnie | |
| Kang Hye-won | Musical Guest | Iz*One - Hyewon | |
| Heo Hyun-joon | Musical Guest | The Boyz - Hwall | |
| Jung Hae-in | Host | Main host & presenter for MAMA Professional Categories and New Challenger Performance | |
| Lee Ki-woo | Guest Star | Presenter for Best New Asian Artist (Thailand & Vietnam) | |
| Hong Jong-hyun | Guest Star | Presenter for Best New Artists | |
| Ji Soo | Guest Star | Presenter for Best New Asian Artist (China, Indonesia & Japan) | |
| Kim So-hyun | Guest Star | Presenter for DDP Best Trend Award | |
| Jung Chae-yeon | Guest Star | Presenter for Best New Asian Artist (China, Indonesia & Japan) | |
| Kang Seung-hyun | Guest Star | Presenter for Best of Next Award | |
| Bae Yoon-kyoung | Guest Star | Presenter for Best New Asian Artist (Thailand & Vietnam) | |
| Kim Yoo-ri | Guest Star | Presenter for Best New Artists |