Under the orders of Hell, the hot-blooded high school is occupied by Sabu and his friends, who come to take the white uniform by force. Not only that, Sabu hypnotized Kunio's friend Hiroshi and turned him into a human weapon. Kunio finds himself in a tight spot. However, Kunio's former enemies, learning of his predicament, gather one after another at Nekketsu High School!
ヘルの命を受け、白ランを力づくで奪いに来たさぶたちに占拠されてしまう熱血高校。そればかりか、さぶはくにおの友人ひろしに催眠術をかけ、人間兵器に仕立て上げていた。次第に窮地に追い込まれていくくにお。だが、そんなくにおのピンチを知ったかつての仇敵が熱血高校に続々と集結!