Searching for the cure for cancer, a scientist creates a chemical that promotes cell growth. After being visited by a drug addict, the drugs and the cure are mixed up and misused by him and several prostitutes. They become zombified and begin biting people nearby. A small group of exotic dancers team up with the prostitutes' former pimp to defend their strip club, the Grindhouse, against a horde of blood-thirsty zombies.
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