After graduating from medical school, Dr. James Kildare (Lew Ayres) returns to his small home town, where his proud parents Stephen (Samuel S. Hinds) and Martha Kildare (Emma Dunn) and childhood friend Alice Raymond (Lynne Carver) expect him to join his father in his medical practice. However, he is more ambitious, though he is unsure what he wants to do. He has accepted a job as an intern at Blair General, a large New York City hospital.
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