The film takes place in and around a film production company office, and involves several interweaving plot threads which include a young actress named Rose (Salma Hayek) who tries to score a screen test from her secret boyfriend Alex Green (Stellan Skarsgård), a noted but disillusioned director. Meanwhile, Rose's tryst with him is discovered by her girlfriend Lauren (Jeanne Tripplehorn), an insanely jealous businesswoman who plants a microphone in Rose's purse and spends most of the time in the back of her limousine parked outside the office building listening in on Rose's conversations. Elsewhere, Alex's wife Emma (Saffron Burrows) is seen with a therapist (Glenne Headly) debating about asking him for a divorce. In the meantime, numerous film industry types (played by Xander Berkeley, Golden Brooks, Holly Hunter and Kyle MacLachlan), pitch ideas for the next big hit film.
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