The film opens with Brad (Rory Cochrane), an out-of-work musician, making coffee for his wife, Lexi (Mary McCormack), who is still in bed. She leaves for work and Brad is left home alone. Over the radio, he hears that several suspected dirty bombs have been detonated across Los Angeles. He exits his house and sees large amounts of smoke rising from the city. Brad gets into his car and drives to the city to find Lexi. Brad tries to contact her through her cell phone, but only receives a busy signal. He soon finds that all roads now have blockade.
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