The Last Mystery of the 20th Century, also known as "Osamu Tezuka's Strangest Case in the 20th Century" has an all-star cast of Tezuka's most famous characters. Osamu Tezuka is invited to a new years party at a mansion owned by Dr. Tenma, and the guests attending the party are all of Osamu Tezuka's creations, suddenly Mr. Tezuka disappears and it quickly becomes a mystery special, with all of his most famous characters trying to find him before the rest of the guests show up.
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Osamu Tezuka (手塚 治虫, born 手塚 治, Tezuka Osamu; 3 November 1928 – 9 February 1989) was a Japanese manga artist, cartoonist, and animator. Born in Osaka Prefecture, his prolific output, pioneering techniques, and innovative redefinitions of genres earned him such titles as "the Father of Manga" (マンガの父, Manga no Chichi), "the Godfather of Manga" (マンガの教父, Manga no Kyōfu) and "the God of Manga" (マンガの神様, Manga no Kami-sama). Additionally, he is often considered the Japanese equivalent to Walt Disney, who served as a major inspiration during Tezuka's formative years.
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