Quando a Rainha recebe uma misteriosa ameaça de morte, o detetive Sherlock Holmes e o seu ajudante Dr. John Watson não olharão a meios estapafúrdios para resolver o caso.
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Nem com lupa eles lá vão.
Ha habido un asesinato en el Palacio de Buckingham y, dentro de cuatro días, la Reina Victoria será la próxima víctima si nadie puede evitarlo. Por suerte para ella, Sherlock Holmes y John Watson se pondrán manos a la obra para frenar de una vez a James Moriarty e impedir que lleve a cabo su terrible plan. O al menos lo intentarán, porque esta no es una historia convencional de Sherlock Holmes. Esto es Holmes & Watson.
In 1881, Sherlock Holmes meets and befriends Dr. Watson. Years later, Holmes is viewed as a legendary detective. Both he and Watson are to view the trial of Professor James Moriarty, but are temporarily waylaid by a package sent by Moriarty and brought to them by their housekeeper, Mrs. hudson. Once at the trial, Holmes declares that the man on trial is not Moriarty and is instead someone named Jacob Musgraves, who is incapable of committing the murders due to tremors in his hand caused by excessive masturbation. Despite unsuccessful attempts by Inspector Lestrade to convince Holmes that his deduction is incorrect, Holmes is convinced that Moriarty is currently traveling to the United States.
Quando la regina riceve un'oscura minaccia di morte, il detective Sherlock Holmes e il suo assistente, il dottor John Watson, usano metodi bizzarri per chiudere il caso.
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