A vapid and dim-witted, but good-natured model named Derek Zoolander, teams up with his upstart rival Hansel to foil a bizarre and far-reaching assassination plan secretly overseen by a prominent fashion guru.
At Fashion Interpol, a secret agent, Valentina Valencia examines the expressions of recently assassinated pop singers' last images and believes they match Derek Zoolander's signature look, "Blue Steel". A flashback reveals that the ''Derek Zoolander Center For Kids Who Can't Read Good'' collapsed, killing Matilda Jeffries and injuring Hansel McDonald. Derek later lost custody of his son, Derek Zoolander Jr., and announced his retirement from modeling and subsequent reclusion.