Jack Conrad is awaiting the death penalty in a corrupt Central American prison. He is "purchased" by a wealthy television producer and taken to a desolate island where he must fight to the death against nine other condemned killers from all corners of the world, with freedom going to the sole survivor.
Similar to the first movie, the protagonist Will (Randy Orton) finds himself in a game of death with several other contestants and is forced to rely on his skills and wits to survive.