And Shepherds we shall be For Thee my Lord, for Thee Power hath descended forth from Thy hand Our feet may swiftly carry out Thy commands. So we shall flow a river forth to Thee And teeming with souls shall it ever be. In nomine Patri, et Filii, et Spiritus Sancti.
Tired of the crime overrunning the streets of Boston, Irish Catholic twin brothers Conner and Murphy are inspired by their faith to cleanse their hometown of evil with their own brand of zealous vigilante justice. As they hunt down and kill one notorious gangster after another, they become controversial folk heroes in the community. But Paul Smecker, an eccentric FBI agent, is fast closing in on their blood-soaked trail.
After the McManus brothers, Connor and Murphy, and their father, Noah (Il Duce), assassinated Joe Yakavetta, they fled to Ireland. Eight years later, their uncle Father Sibeal arrives to inform them that a renowned Boston priest was murdered by a mysterious assassin who attempted to frame the Saints by using their ritual assassination style. In response, the brothers dig up their old gear and weapons and depart for the United States.