The series is about a fictitious university, Blue Mountain State, and its football team, the "Mountain Goats". It portrays certain aspects of American university life, including college football, sex, binge drinking, drugs, wild partying, and hazing.
Three incoming freshmen attending Midwestern college football powerhouse Blue Mountain State must quickly adapt to college life and juggle football, girls, classes and nonstop hazing.
When a new dean threatens to take over the Goat House, the party location for the school's football team, Alex Moran reaches out to Thad Castle, who has recently been drafted into the NFL, to buy the house. Thad agrees he will, but only if Alex throws a party in his honor and it meets his wild expectations. The party, full of drugs and amusement rides, gets out of hand, but Thad is impressed nevertheless.