1967 - John Form, a doctor, presents his expectant wife Mia with a rare vintage porcelain doll as a gift for their first child to be placed in a collection of dolls in their daughter's nursery. A couple begins to experience terrifying supernatural occurrences involving a vintage doll shortly after their home is invaded by satanic cultists.
1955 - Several years after the tragic death of their little girl in 1943, a doll maker and his wife welcome a nun and several girls from a shuttered orphanage into their home, soon becoming the target of the doll maker's possessed creation—Annabelle.
1972 - Determined to keep Annabelle from wreaking more havoc, demonologists Ed and Lorraine Warren bring the possessed doll to the locked artifacts room in their home in 1970, placing her “safely” behind sacred glass and enlisting a priest’s holy blessing. Through the next years Annabelle awakens the evil spirits in the room, who all set their sights on a new target—the Warrens' ten-year-old daughter, Judy, and her friends.