Larry Talbot returns to his father's castle in Wales and meets a beautiful woman. One fateful night, Talbot escorts her to a local carnival where they meet a mysterious gypsy fortune teller.
Some four years after the events of ''The Wolf Man'' and ''The Ghost of Frankenstein'', two men break into the Talbot family crypt to open the grave of Larry Talbot (Lon Chaney, Jr.), seeking jewelry buried with him, on the night of a full moon. During the robbery, the thieves remove the Aconitum buried with Talbot, and he is awakened from death by the full moon shining on his uncovered body. Talbot reflexively grasps the arm of the grave robber with a fur-covered hand, as the other thief flees.