In the near future, illegal androids have become commonplace, and many criminals will enhance themselves with cybernetic components, making them "more than human". Alex Raine (Olivier Gruner) is a disillusioned assassination for the Los Angeles Police Department. During a routine mission, he is attacked by a group of cyborg freedom fighters known as The Red Army Hammerheads. Nearly killed by the surviving leader, Rosaria (Jennifer Gatti), Alex resists her assertion that he is a mindless robot: "Eighty-six point five percent [of him] is still human."
73 years after Alex failed, humans have lost the Cyborg Wars and they are now slaves to the cyborg masters. Rebel scientists have developed a new DNA strain, which could signal the end of the cyborgs, and it is injected it into a pregnant volunteer.
Alex (Sue Price) wakes up in the desert with a bullet in the back of her head and total amnesia. Following her footprints back the way she came, she encounters a man named Farnsworth 2 (Tim Thomerson, reprising his role from the original film), who offers to help her and get her medical attention. He gives her "a shot of endo" to repair the affected part of her brain and she starts to have flashes of memories; when she remembers a woman warning her not to let Farnsworth 2 get her DNA, she kills him with his own gun before he can complete a blood test on her. She then passes out and begins to remember...