In Piqua, Ohio, George Beard and Harold Hutchins are two fourth-grade friends and next-door neighbors who often bring joy to their school, Jerome Horwitz Elementary School, by excessively pranking the cruel teachers, especially the mean Principal Benjamin "Benny" Krupp, which puts them at odds with him. The duo also create comic books about a superhero named Captain Underpants, a character who has superpowers and wears underwear and a cape. They sell these to their schoolmates through a comic company called Treehouse Comix Inc, housed in their treehouse. George and Harold's pranks come to an apparent end after they tamper with a toilet invention, the Turbo Toilet 2000, made by the school's local snitch, intellectual Melvin Sneedly. This causes Mr. Krupp to decide to separate the boys and annihilate their friendship.
Adventurous fourth-graders and comic book artists George Beard and Harold Hutchins, bring to life Captain Underpants -- a brief-wearing superhero.
When Melvin tries to cancel Halloween, clever best friends Harold and George create their own spooky holiday -- and it's a huge success.
Basically, this is an adventure where fourth-graders Harold Hutchins and George Beard try to get the best of their evil principal Mr. Krupp by turning him into Captain Underpants. But this adventure is interactive.
Best friends George and Harold — along with their classmates and tyrannical principal — are recruited for a mysterious mission in outer space.
Christmas gets weird - really weird - after George and Harold go back in time to change up a few of their beloved holiday's traditions.