David Banner is a research scientist trying to find a way to tap into the hidden strength that all humans possess. Then, one night in his labratory, an experiment went wrong, causing him to be overexposed to gamma radiation. Now, whenever angered or distressed, the mild-mannered scientist finds himself transforming into a powerful seven-foot green creature known as The Incredible Hulk. The Hulk is guided by David's personality, dealing with whatever distresses David. But unfortunately, David has no control over the creature's actions. Nor can he remember what he had done during his Hulkish states. He travels around the country in search of a cure, while taking various odd jobs under different aliases.
At Culver University in Virginia, General Thunderbolt Ross meets with Dr. Bruce Banner (Marvel Cinematic Universe), the colleague and boyfriend of his daughter Betty Ross, regarding an experiment that Ross claims is meant to make humans immune to gamma radiation. The experiment—part of a World War II-era Weapon Plus that Ross hopes to recreate—fails, and the exposure to gamma radiation causes Banner to transform into the Hulk for brief periods of time, whenever his heart rate rises above 200 beats per minute. The Hulk destroys the lab and surrounding area, killing several people inside, and injuring the General and Betty, along with others outside. Banner becomes a fugitive from the U.S. military and Ross in particular, who wants to weaponize the Hulk.
On the run and presumed dead by the authorities, David Banner, using the name 'Benton', continues in his efforts to find a cure. He accidentally finds himself in the middle of a plot to kill a young, crippled girl so her unscrupulous relatives can inherit the family fortune.
Dr. David Banner meets a former student, who has a magical hammer that summons Thor, a Norse god who is prevented from entering Valhalla. When the two superheroes stop feuding long enough to breathe, they are a team unmatched by any of their enemies.
On the run again after the events of The Incredible Hulk Returns, A disenchanted and overwhelmed David Banner is working up north under the name David Belson. A bully pushes him around and David tempts to fight him back, but knowing he'll just turn into the Hulk again, he throws the fight and walks away.
David Banner (Bill Bixby) masquerades as David Bellamy, a mentally challenged janitor, to gain access to a scientific research facility in Portland, Oregon. He believes that the studies of one of the scientists there, Dr. Ronald Pratt (Philip Sterling), may hold the key to curing his gamma ray-induced condition that, in times of stress, turns him into a superhuman green creature known as the Hulk.
