The mice of the Rescue Aid Society saving the day.
Join the shy but brave mouse Bernard and his glamorous partner Miss Bianca – two tiny heroes on a great big mission to save a young girl named Penny, who has sent an urgent call for help. Taking off on the wings of their trusted albatross friend Orville, Bernard and Bianca soar to the marshy swamp of Devil's Bayou. There, they find themselves on the riverboat hideout of Madame Medusa, who needs Penny to retrieve the world's largest diamond.
The R.A.S. agents, Miss Bianca and Bernard, race to Australia to save a little boy and a rare golden eagle from a murderous poacher.